Valium is a tranquilizer that belongs to the group of benzodiazepines. Overdose of Diazepam is dangerous for both mental and physical health. Therefore, you need to talk to your doctor before starting treatment with diazepam. The WHO has listed Valium as one of its “Essential Medicines”.

Drug NamePackagePer ItemGo Pharmacy
Generic Valium10 mg$2.90Go To Pharmacy

Active ingredient and clinical pharmacology

Valium contains the active ingredient diazepam, which belongs to a group of benzodiazepines. These are psychoactive substances affecting central nervous system. Their effect can be both positive and negative. Benzodiazepines have the following effects on the nervous system:

  • sedative;
  • soothing;
  • anxiolytic (anti-anxiety);
  • anticonvulsant;
  • amnestic (loss of memory).

In addition, diazepam can increase the clinical effects of some other medicines (including sedatives, painkillers, neuroleptics and narcotic drugs), as well as alcohol. Long-term use of Valium can lead to the development of addiction.

Diazepam works by potentiating the actions of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the brain. Diazepam is rapidly absorbed from the gastrointestinal tract and excreted mainly in the urine.

Indications

Valium oral is used for the treatment of:

  • neurotic behaviors (mono- and complex therapy), including anxiety and hypochondriac disorders, hysteria, neurasthenia;
  • mono- and complex therapy of organic brain disorders, psychosis and dysphoria;
  • severe insomnia;
  • complex therapy of status epilepticus;
  • as part of treatment for schizophrenia and phobic disorders;
  • psychosomatic disorders;
  • premedication for patients undergoing surgical procedures.

Injection form of Valium is used for the treatment of acute neuropsychiatric disorders, panic attacks, anxiety, epileptic seizures accompanied by severe paralysis and emotional manifestations. Other indications include alcohol withdrawal and delirium tremens.

Valium is indicated for the treatment of neurosis and neurotic disorders (which can be accompanied by urinary incontinence, headache and behavioral disorders) in children.

Contraindications

Valium is contraindicated in patients with:

  • hypersensitivity to benzodiazepines or any components of the drug;
  • suicidal tendencies;
  • myasthenia gravis;
  • history of drug or alcohol abuse (the only exception is withdrawal syndrome);
  • cardiac and respiratory failure, sleep apnea syndrome;
  • closed-angle glaucoma.
  • Caution should be exercised when administering Valium to:
  • elderly patients;
  • children under 3 years of age.

Dosage and administration

Valium tablets can be taken with or without food. Dosage should be determined individually based on the nature and severity of the patient’s disease.

Management of anxiety disorders: 2.5−10 mg, 2 to 4 times daily.

Treatment of neurosis: 5−10 mg 2 to 3 times daily.

Children over 3 years of age: 2.5 mg daily. In this case, Valium should be prescribed at the lowest effective dose for the shortest duration possible.

Side effects

Valium can cause some side effects. The most common of them include:

  • nervous system: drowsiness, muscle weakness, mood swings, sleep disorders, depression, hallucinations, ataxia, tremor, headache and confusion;
  • digestive system: hypersalivation, change in stool consistency and frequency, jaundice, sickness and dry stool;
  • visual impairment;
  • changes in libido;
  • urinary incontinence;
  • respiratory failure;
  • joint pain;
  • skin rash and itching;
  • local inflammation (in case of injection use).

Long-term use of Valium can lead to addiction and withdrawal symptoms after discontinuation of treatment.

First aid for Valium overdose

Overdose of Valium may lead to areflexia, respiratory failure, cardiorespiratory depression, apnea and coma. Patients may require immediate gastric lavage, as well as the use of sorbents and a specific antidote called flumazenil. In some cases, mechanical ventilation may be needed.

In recent years, there has been a rise in the prevalence of anxiety disorders across the globe. The COVID-19 crisis has further made it even more difficult for individuals already suffering from pre-existing conditions to cope with the psychological pressures that come with living in a pandemic. Trying to function without spiraling down a cycle of negative thoughts while constantly being exposed to stressful situations in real life or even in the news is becoming increasingly difficult for many. One way being explored through studies to help reduce symptoms of anxiety in individuals is the use of Medical Marijuana products as they produce a calming effect within our body. If appropriately used after consultations with expert physicians working with Medical Marijuana, it can be very beneficial in elevating symptoms like loss of sleep and promoting a more relaxed and positive state of mind.

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Anxiety.

What is Anxiety?

Anxiety is a word that is used very often and is thought of as being synonymous with ‘daily-life stress,’ but in reality, an anxiety disorder is much more intense. It can significantly impact the life functioning of an individual diagnosed with it. Anxiety disorders often create an overwhelming sense of worry, concern, or fear in a person, resulting in avoidance of places or situations which act as triggers. It can be a debilitating illness that hinders growth in all areas of life; social relationships, academics, occupation, and career.

Oftentimes, the repetition of worry-stricken thoughts is accompanied by physical symptoms such as tiredness and fatigue, difficulty sleeping, the inability to focus or concentrate, nausea and dizziness, muscle tension, and more. There are different types of disorders that come under the umbrella of anxiety disorders, such as agoraphobia, GAD, panic disorder, and more. Each anxiety disorder has specific symptoms that need to be present for a proper diagnosis. What remains common in all is the feeling of restlessness, uncontrollable thoughts, and fear which greatly impact the quality of life of the person diagnosed. While several therapy treatments and medications exist for treating anxiety disorders, sometimes the medicines can cause unpleasant side effects in some people. So, it is preferred to go for a combination and see what works best. Medical Marijuana can be added to the already existing plan to further reduce the symptoms and aid in uplifting the patients’ mood and improving their well-being.

How Does Medical Marijuana Help with Anxiety?

To understand how Medical Marijuana can help with anxiety, it is essential to delve into the scientific composition of the drug. Cannabis is composed of more than 200 different compounds and ingredients, CBD (cannabidiol) and THC (tetrahydrocannabinol) being the two most abundant ones. The component which is psychoactive in nature and responsible for causing the marijuana-induced high is THC, whereas CBD is more commonly used for various therapeutic purposes and is a non-psychoactive compound. In our bodies, we have what is called the endocannabinoids system (ECS), which comprises a network of neurotransmitters and receptors which enable our brain and our body to communicate with each other.

THC and CBD both have a chemical structure similar to that of our body’s endocannabinoids and so are able to attach to certain receptors within the endocannabinoids system. This interaction causes the release of neurotransmitters in the brain, which are responsible for regulating things like our concentration, appetite, moods, stress, sleep, amongst other things. This interaction is what enables Medical Marijuana to be able to play a role in improving symptoms of anxiety.

Choosing The Right Medical Marijuana Products for Anxiety :

Marijuana Product.

Some studies have shown that CBD containing products may affect the levels of serotonin in the brain. Most medications, such as antidepressants, also work by regulating the serotonin levels in the body, but more research is being conducted to explore if CBD also works in a similar way. However, products that are specifically CBD dominant are preferred over products that have too much THC when dealing with anxiety. This is because products containing a high level of THC can increase rather than reduce anxiety due to an increase in stimulation, triggering some anxiety symptoms such as increased heart rate and rapid thoughts.

Hence, making sure that one buys the correct type of Medical Marijuana product, which will prove to be beneficial for you, is of utmost importance. By choosing our service at My Florida Green and accessing a Medical Marijuana card Naples, you can guarantee that you will choose the right product for yourself by taking help from our team of experts who know the science behind all Medical Marijuana products present in the market and can guide you in making the right choice.